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Restrictions during the COVID-19 pandemic significantly affected people's opportunities to engage in activities that are meaningful to their lives. In response to these constraints, many people, including older adults, turned to digital technologies as alternative ways to pursue meaningful activities. These technology-mediated activities, however, presented new challenges for older adults' everyday use of technology. In this paper, we investigate how older adults used digital technologies for meaningful activities during COVID-19 restrictions. We conducted in-depth interviews with 40 older adults and analyzed the interview data through the lens of self-determination theory (SDT). Our analysis shows that using digital technologies for meaningful activities can both support and undermine older people's three basic psychological needs for autonomy, competence, and relatedness. We argue that future technologies should be designed to empower older adults' content creation, engagement in personal interests, exploration of technology, effortful communication, and participation in beneficent activities. © 2023 ACM.
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In order to analyze the impact of COVID-19 prevention and control measures on the hotspots of residential burglary, the data of crimes that occurred during the First Level Response period of Major Public Health Emergencies in Beijing in 2020 and the same period in 2019 were collected, and the changes of hotspots during the two periods were compared by using kernel density estimation and predictive accuracy index. Consequently, the environmental features such as street network, point of interest (POI) diversity, crime locations, and repeat victimization in significantly varied hotspot areas were investigated. The results show that: 1) After the outbreak of the pandemic, the occurrence of residential burglary in the core urban areas of Beijing dropped significantly, and daily occurrence of crimes during the First Level Response period in 2020 decreased by 66.8% compared with the same days in 2019. 2) The eight major hotspots that existed in 2019 apparently declined during the corresponding days in 2020, five of them basically disappeared, and three hotspots weakened. 3) The declined hotspots were generally clustered around traffic hubs, areas with high diversity of POIs, clustered crimes, and repeat victimizations. 4) Home isolation and social restriction strategies implemented during the First Level Response period reduced the opportunities of offenders, and the real-name inspection adopted in public places increased the exposure risk of offenders, which are the main reasons for the hotspots decline during the pandemic. This work has some implications for crime prevention and police resources optimization during the pandemic. © 2023, Editorial office of PROGRESS IN GEOGRAPHY. All rights reserved.
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Background & Aim: With larger accessibility and increased number of patients being treated with CART cell therapy, real-world toxicity continues to remain a significant challenge to its widespread adoption. We have previously shown that allogeneic umbilical cord blood derived (UCB) regulatory T cells (Tregs) can resolve uncontrolled inflammation and can treat acute and immune mediated lung injury in a xenogenic model as well as in patients suffering from COVID-19 acute respiratory distress syndrome. The unique properties of UCB Tregs including: i) lack of plasticity when exposed to inflammatory micro-environments;ii) no requirement for HLA matching;iii) long shelf life of cryopreserved Tregs;and iv) immediate product availability for on demand treatment, makes them an attractive source for treating acute inflammatory syndromes. Therefore, we hypothesized that add-on therapy with UCB derived Tregs may resolve uncontrolled inflammation responsible for CART cell therapy associated toxicity. Methods, Results & Conclusion(s): UCB Tregs were added in 1:1 ratio to CART cells, where no interference in their ability to kill CD19+ Raji cells, was detected at different ratios : 8:1 (80.4% vs. 81.5%);4:1 (62.0% vs. 66.2%);2:1 (50.1% vs. 54.7%);1:1 (35.4% vs. 44.1%) (Fig 1A). In a xenogenic B cell lymphoma model, multiple injections of Tregs were administered after CART injection (Fig 1B), which did not impact distribution of CD8+ T effector cells (Fig 1C) or CART cells cells (Fig 1D) in different organs. No decline in the CAR T levels was observed in the Tregs recipients (Fig 1E). Specifically, no difference in tumor burden was detected between the two arms (Fig 2A). No tumor was detected in CART+Tregs in liver (Fig 2B) or bone marrow (Fig 2C). A corresponding decrease in multiple inflammatory cytokines in peripheral blood was observed in CART+Tregs when compared to CART alone (Fig 2D). Here we show "proof of concept" for add-on therapy with Tregs to mitigate hyper-inflammatory state induced by CART cells without interference in their on-target anti-tumor activity. The timing of Tregs administration after CART cells have had sufficient time for forming synapse with tumor cells allows for preservation of their anti-tumor cytotoxicity, such that the infused Tregs home to the areas of tissue damage to bind to the resident antigen presenting cells which in turn collaborate with Tregs to resolve inflammation. Such differential distribution of cells allow for a Treg "cooling blanket" and lays ground for clinical study. [Figure presented]Copyright © 2023 International Society for Cell & Gene Therapy
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Covid-19 virus variants identified so far are due to viral genetic diversity, genetic evolution, and variable infectivity, suggesting that high infection rates and high mortality rates may be contributed by these mutations. And it has been reported that the targeting strategies for innate immunity should be less vulnerable to viral evolution, variant emergence and resistance. Therefore, the most effective solution to Covid-19 infection has been proposed to prevent and treat severe exacerbation of patients with moderate disease by enhancing human immune responses such as NK cell and T cell. In previous studies, we demonstrated for the first time that gamma-PGA induced significant antitumor activity and antiviral activity by modulating NK cell-mediated cytotoxicity. Especially intranasal administration of gamma-PGA was found to effectively induce protective innate and CTL immune responses against viruses and we found out that gamma-PGA can be an effective treatment for cervical intraepithelial neoplasia 1 through phase 2b clinical trial. In this study, the possibility of gamma-PGA as a Covid-19 immune modulating agent was confirmed by animal experiments infected with Covid-19 viruses. After oral administration of gamma-PGA 300mug/mouse once a day for 5 days in a K18-hACE2 TG mouse model infected with SARS-CoV-2 (NCCP 43326;original strain) and SARS-CoV-2 (NCCP 43390;Delta variant), virus titer and clinical symptom improvement were confirmed. In the RjHan:AURA Syrian hamster model infected with SARS-CoV-2 (NCCP 49930;Delta variant), 350 or 550 mug/head of gamma-PGA was administered orally for 10 days once a day. The virus for infection was administered at 5 x 104 TCID50, and the titer of virus and the improvement of pneumonia lesions were measured to confirm the effectiveness in terms of prevention or treatment. In the mouse model infected with original Covid-19 virus stain, the weight loss was significantly reduced and the survival rate was also improved by the administration of gamma-PGA. And gamma-PGA alleviated the pneumonic lesions and reduced the virus titer of lung tissue in mice infected with delta variant. In the deltavariant virus infected hamster model, gamma-PGA showed statistically significant improvement of weight loss and lung inflammation during administration after infection. This is a promising result for possibility of Covid-19 therapeutics along with the efficacy results of mouse model, suggesting gammaPGA can be therapeutic candidate to modulate an innate immune response for Covid-19.
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Playability is an attribute that refers to the ability to stimulate individual responses or collective action in an immersive activity in an exploratory way. Playability is an important component of the enjoyment and well-being of urban dwellers, has the potential to stimulate urban vitality and is an important expression of the inclusiveness and equity of urban space. The pursuit of economic development and efficiency-oriented urban construction has led to the domination of urban space by overcrowded traffic, economy-oriented commerce and densely populated housing. Moreover, the existence of playable space has become a scarce resource and is seen as a site for the materialisation of social rights. As the haze of the COVID-19 pandemic fades and cities are again exposed to wider and more participatory use, determining how to adapt urban spaces to the playability needs of users of different ages, cultural backgrounds and social classes, and provide them with appropriate site use and experience, is becoming a hot issue of concern for building equitable and high-quality urban spaces. The study of the playability of urban spaces is highly complex, and the related research on social justice is cryptic. In order to better investigate the social equity aspects of urban playability, this paper integrates scientometric and manual methods to review the relevant research. This paper takes 2664 related papers from the Web of Science (WOS) core dataset from 1998 to 2022 as the research object and employs CiteSpace to organise the existing research results of playful urban spaces. Quantitative analysis is used to clarify the theoretical foundations, developments and research hotspots of urban spatial playability, while the manual collation and generalisation of the studies uncover the hidden issues of social justice research. Based on the proposed research method, we summarize the key three research stages related to urban spatial playability and social equity. We also discuss the development of urban spatial playability in the perspective of social justice from three aspects: micro, meso and macro. The results can help readers better understand the current status and development process of research on playful urban space. In particular, we clarify the issues related to social justice under the theme of the playability of urban spaces and provide directions for future research on building playful cities and promoting the development of urban socio-spatial equity.
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Compound Qinlan Oral Liquid (,CQOL) is derived from Yinqiao San (), which is composed of Jinyinhua (Lonicerae Japonicae Flos), Huangqin (Scutellariae Radix), Lianqiao (Forsythiae Fructus) and Banlangen (Isatidis Radix). It is a common clinical herbal medicine for clearing heat and detoxification, and has antiviral effects. By reviewing the active ingredients of CQOL and the research progress on its anti-influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) efficacy, with view to providing a basis for the clinical use of CQOL in treatment of respiratory diseases caused by SARS-CoV-2.Copyright © 2023 Editorial Office of Chinese Traditional and Herbal Drugs. All rights reserved.
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Objective: Alcohol Use Disorder (AUD) is a common, chronically relapsing condition with substantial health and economic costs. United States federal agencies have put out calls in the last decade to expand the scientific evidence base for broad biopsychosocial recovery from AUD and other substance use disorders (SUD). The present study examined the role of physical activity and exercise in early recovery from AUD, with specific attention to changes in brain-derived neurotrophic factor (BDNF) as a marker of neuroplasticity and a potential mechanism for instantiation of recovery-aligned behaviors. Method: Individuals in the first year of recovery from AUD were recruited into a 12-week study with exercise sessions and pre/post-exercise blood sample collection performed in a laboratory setting at baseline, 6 weeks, and 12 weeks. Data analyses included BDNF enzyme-linked immunosorbent assays (ELISA) to establish pre/post-exercise BDNF concentrations, estimation of the magnitude of the effect of exercise on BDNF, and prospective associations of exercise-induced BDNF change with coping, craving, consumption and mood outcome measures. Results: 26 participants were screened, 22 were eligible, 7 had entered the study, and 6 had provided at least one set of pre/post-exercise blood samples when student research ceased on March 23rd, 2020 due to COVID-19 precautions. Participants with at least one set of pre/post-exercise blood samples demonstrated a statistically significant (p=.014) increase from baseline in BDNF levels after exercise, with a large effect size (Cohen's d=1.519;Hedges' g=1.019 ). The impact of this increase from baseline on subsequent measures of coping, craving, mood, and substance use is unclear due to lack of statistical power. Conclusions: This study is the first to demonstrate that individuals recovering from AUD can increase serum levels of BDNF from baseline levels via sessions of physical exercise. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
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The COVID-19 pandemic has impacted society: causing the collapse of health systems around the world, and also had a significant impact on the economy, personal care, mental health and the quality of life of the population. Few studies have been done about pandemic and the climacteric population, and the impact on quality of life and health. Our objective was to Investigate changes in the health and health care of climacteric women residing in Brazil during the pandemic period. Cross-sectional study with climacteric women aged between 40 and 70 years, residing in Brazil. The evaluation was carried out using a Google Docs electronic form with questions related to sociodemographic, clinical, gynecological data, treatments, access to health services and consultations, as well as changes in behavior. The Menopause Rating Scale - MRS was applied to assess climacteric symptoms, validated for Portuguese. Result(s): 419 women answered the questionnaire. More than 45% were between 51 and 60 years of age, 56.6% being married and residing in Brazilian capitals. 60% of participants reported weight gain during the pandemic. 50.8% of participants reported a decrease in the weekly practice of physical activity More than 80% reported worsening mental health during this period, and 66.1% had a change in their sleep pattern. More than half reported having difficulty accessing gynecological consultations. Women living in capital cities reported a greater increase in alcohol consumption (p=0.002). Food intake increased for 54.9%;the category of civil servant was associated with a significant increase in consumption in relation to other professions (p=0.038). Women whose family incomes changed during the pandemic had a higher prevalence of weight gain (p=0.033) and also had a higher occurrence of changes in sleep quality (72.6% vs. 61.5%;p=0.018). Women with a high school education had a higher occurrence of alterations in personal and health care outcomes (p<0.001). Conclusion(s): We observed an important reduction in the health care of climacteric women during the pandemic period. Changes in life habits, such as increased food consumption and reduced physical activity, were quite prevalent. There was a deterioration in mental health, with a high prevalence of anxiety symptoms and changes in sleep quality. Despite the attenuation of the pandemic, attention should be given to the health care of this population, as the changes may have repercussions for many years.Copyright © 2023
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Background During the containment of COVID-19，the traditional face-to-face interventions conducted at the rehabilitation center were plagued by many limitations，while internet-based interventions can overcome the limitations of geographic location，working hours and transportation，with less medical costs. Objective To examine the effects of internet-based interventions on knowledge，attitude/belief and practice（KAP） toward rehabilitation exercises，physical activity（PA）level，and exercise compliance inpatients after PCI. Methods The subjects were 76 patients who received their first PCI in Department of Cardiology，Tangshan Gongren Hospital from November 2021 to June 2022. They were randomly and equally divided into two groups to receive either internet-based intervention with routine nursing（experimental group） or routine nursing （control group）. Before and three months after the intervention，the Rehabilitation Exercise Knowledge-Belief-Practice Scale for Patients with Coronary Heart Disease（REKBPCHD），the International Physical Activity Questionnaire-Short Form （IPAQ-SF），and Patients' Exercise Log were used to assess the KAP level，PA level，and exercise adherence，respectively. The impact of network intervention on exercise adherence in patients after PCI by univariate Logistic regression analysis. Results After 3 months of intervention，a significant increase was found in the average total score of REKBPCHD，and the average scores of the knowledge dimension，attitude dimension and practice dimension of the scale in the experimental group（P<0.05），and the increase was more notable than that in the control group（P<0.05）. Moreover，both post-intervention low PA level and total PA level in the experimental group were higher than those in the control group（P<0.05）. Both post-intervention low PA level and total PA level were higher than the baseline levels in the experimental group（P<0.05）. The post-intervention exercise compliance of experimental group were higher than that in the control group（P=0.003）. Univariate Logistic regression analysis showed that the risk of non-adherence to exercise in the experimental group was relatively lower than that in the control group 〔OR=0.143，95%CI（0.034，0.594），P=0.007〕. Conclusion Theinternet-based intervention can effectively improve the KAP level toward rehabilitation，PA level，and exercise adherence in patients after PCI. © 2023 Chinese General Practice. All rights reserved.
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This chapter explores the major lessons learned from the COVID-19 pandemic, which has strongly influenced collaboration in almost all private and public organizations. Hybrid collaboration refers to the balance between onsite and remote collaboration in such a way that organizational performance, employee involvement and innovativeness can be optimized. When we focus on different levels of aggregation, it is proposed that different balances of hybrid work collaboration are needed at the level of teams, the internal organization, and the organization in relation to its external stakeholders (ecosystem). Such a hybrid collaborating organization requires a multidisciplinary understanding and effort in which (top) management, employees, and other internal and external stakeholders share knowledge, interact, and work together to generate benefits, both tangible and intangible, that an organization can provide to what relevant stakeholders actually value. In conclusion, some dilemmas that most organizations have to deal with during their journey toward shaping hybrid collaboration organizations will be discussed. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.
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The aim of this study is to determine the motivation of high school students to participate in physical activity and their eating attitude levels during the COVID-19 period as well as to examine the relationship between the two variables. In addition, it was also determined whether the motivation for participate in physical activity and eating attitudes differ according to gender, weekly exercise, spending time with technology, family communication times, and participation in exercise during and before the pandemic. A total of 576 high school students, including 406 girls and 170 boys, participated in the study. "Motivation Scale for Participation in Physical Activity (MSPPA)", "Eating Attitude Test (EAT-40)" and "Personal Information Form (KBF)" were used as data collection tools. Data were evaluated using correlation, multiple linear regression, MANOVA and t-test analysis techniques. It was concluded that the motivation of the students to participate in physical activity was moderate, and they did not have eating disorders. It was observed that physical activity motivation did not predict eating attitude, but there were positive and low relationships between sub-factors in relational dimension. According to gender, it was determined that the eating attitudes of female students were more positive than male students. It has been found that the motivation to participate in physical activity is higher for those who exercise before and during the pandemic than those who do not. Consequently, it can be said that during the COVID-19 process, high school students' motivation to participate in physical activity is at a moderate level, and their eating attitudes are generally not at the level of behavioral disorders.
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PurposeThis paper aims to identify key factors for a contextualised Systemic Risk Governance (SRG) framework and subsequently explore how systemic risks can be managed and how local institutional mechanisms can be tweaked to deal with the complex Indonesian risk landscape.Design/methodology/approachUsing a case study from Palu triple-disasters in Central Sulawesi, Indonesia, the authors demonstrate how inland earthquakes in 2018 created cascading secondary hazards, namely tsunamis, liquefactions and landslides, caused unprecedented disasters for the communities and the nation. A qualitative analysis was conducted using the data collected through a long-term observation since 2002.FindingsThe authors argue that Indonesia has yet to incorporate an SRG approach in its responses to the Palu triple-disasters. Political will is required to adopt more appropriate risk governance modes that promote the systemic risk paradigm. Change needs to occur incrementally through hybrid governance arrangements ranging from formal/informal methods to self- and horizontal and vertical modes of governance deemed more realistic and feasible. The authors recommend that this be done by focusing on productive transition and local transformation.Originality/valueThere is growing awareness and recognition of the importance of systemic and cascading risks in disaster risk studies. However, there are still gaps between research, policy and practice. The current progress of disaster risk governance is not sufficient to achieve the Sendai Framework for Disaster Risk Reduction (2015–2030) unless there is an effective governing system in place at the local level that allow actors and institutions to simultaneously manage the interplays of multi-hazards, multi-temporal, multi-dimensions of vulnerabilities and residual risks. This paper contributes to these knowledge gaps.
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Objective: Immunohistochemistry of post-mortem lung tissue from Covid-19 patients with diffuse alveolar damage demonstrated marked increases in chondroitin sulfate and CHST15 and decline in N-acetylgalactosamine-4-sulfatase. Studies were undertaken to identify the mechanisms involved in these effects. Method(s): Human primary small airway epithelial cells (PCS 301-010;ATCC) were cultured and exposed to the SARSCoV- 2 spike protein receptor binding domain (SPRBD;AA: Lys310-Leu560;Amsbio). Expression of the spike protein receptor, angiotensin converting enzyme 2 (ACE2), was enhanced by treatment with Interferon-beta. Promoter activation, DNA-binding, RNA silencing, QPCR, Western blots, ELISAs, and specific enzyme inhibitors were used to elucidate the underlying molecular mechanisms. Result(s): Treatment of the cultured cells by the SPRBD led to increased CHST15 and CHST11 expression and decline in ARSB expression. Sulfotransferase activity, total chondroitin sulfate, and sulfated glycosaminoglycan (GAG) content were increased. Phospho-T180/T182-p38-MAPK and phospho- S423/S425-Smad3 were required for the activation of the CHST15 and CHST11 promoters. Inhibition by SB203580, a phospho-p38 MAPK inhibitor, and by SIS3, a Smad3 inhibitor, blocked the CHST15 and CHST11 promoter activation. SB203580 reversed the SPRBD-induced decline in ARSB expression, but SIS3 had no effect on ARSB expression or promoter activation. Phospho-p38 MAPK was shown to reduce retinoblastoma protein (RB) S807/S811 phosphorylation and increase RB S249/T252 phosphorylation. E2F-DNA binding declined following exposure to SPRBD, and SB203580 reversed this effect. This indicates a mechanism by which SPRBD, phospho-p38 MAPK, E2F, and RB can regulate ARSB expression and thereby impact on chondroitin 4-sulfate and dermatan sulfate and molecules that bind to these sulfated GAGs, including Interleukin-8, bone morphogenetic protein-4, galectin-3 and SHP-2 (Src homology region 2-containing protein tyrosine phosphatase 2). Conclusion(s): The enzyme ARSB is required for the degradation of chondroitin 4-sulfate and dermatan sulfate, and accumulation of these sulfated GAGs can contribute to lung pathophysiology, as evident in Covid-19. Some effects of the SPRBD may be attributable to unopposed Angiotensin II, when Ang1-7 counter effects are diminished due to binding of ACE2 with the SARS-CoV-2 spike protein and reduced production of Ang1-7. Aberrant cell signaling and activation of the phospho-p38 MAPK and Smad3 pathways increase CHST15 and CHST11 production, which can contribute to increased chondroitin sulfate in infected cells. Decline in ARSB may occur as a consequence of effects of phospho-p38 MAPK on RB phosphorylation and E2F1 availability. Decline in ARSB and the resulting impaired degradation of sulfated GAGs have profound consequences on cellular metabolic, signaling, and transcriptional events. Funding is VA Merit Award.Copyright © 2023 The American Society for Biochemistry and Molecular Biology, Inc.
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This study compares the serological antibody level post-COVID-19 vaccine among healthy subjects and psychiatric patients on antidepressant therapy. It also examines the difference in antidepressants' side effects experienced by psychiatric patients following the completion of two vaccine doses. A comparative posttest quasi-experimental study was conducted among healthy subjects and psychiatric patients on antidepressant medication in a teaching hospital in Malaysia. Elecsys Anti-SARS-CoV-2 assay was used to detect the antibody titre between weeks 4 and 12 post vaccination. The antidepressant side-effect checklist (ASEC) was used to monitor the occurrence of antidepressant-related side effects pre-and post-vaccination. 24 psychiatric patients and 26 healthy subjects were included. There was no significant difference in the antibody level between the patients (median = 1509 u/ml) and the healthy subjects (median = 995 u/ml). There was no significant worsening in the antidepressant-related side effects. The antibody level post-COVID-19 vaccine did not differ significantly between patients on antidepressant therapy and healthy subjects. Additionally, there was no change in the antidepressant side effects experienced by the patients following the completion of the vaccine.Copyright © 2022, Research Trends (P) LTD.. All rights reserved.
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Aim: SARS-CoV-2 has caused a global pandemic that has negative consequences for many parts of life. To our knowledge, no study has assessed the effect of the SARS-CoV-2 pandemic on a possible delay in prosthodontic treatments because of a potential concern of contamination in individuals. Therefore, the purpose of this study was to assess this potential impact of fear, as well as oral health-related quality of life, in partially edentulous patients using questionnaires during the SARS-CoV-2 pandemic. Material(s) and Method(s): A total of 135 partially edentulous patients (74 females and 61 males aged 18-70 years) participated in this study. A complete questionnaire consisting of general knowledge questions on SARS-CoV-2 and the OIDP scale, which evaluates the effect of oral status on daily activities were used in participants. Result(s): Statistical analyzes showed that participants with a history of SARS-CoV-2 and/or who are aware of a member of their social circle with a history of the virus, and/or who is deceased, were unwilling to receive dental care during the pandemic. Most of the participants between the ages of 31 and 60 were more worried about the transmission of SARS-CoV-2 during dental treatment. Discussion(s): Concerns about SARS-CoV-2 contamination of patients over 30 years of age may have a negative impact on oral health due to delayed prosthodontic treatments.Copyright © 2022, Derman Medical Publishing. All rights reserved.
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Remote work has been gaining in popularity for years, even before the COVID-19 pandemic began. Along with its perceived benefits, remote work often results in individuals spending long hours at a computer or on the phone. Consequently, remote workers may find that a large portion of their day is spent sitting without taking any kind of break, especially those for physical activity. The purpose of this action research study was to explore proven strategies that enable remote workers to take active breaks during their workday. Data was collected from longtime remote workers during Cycle 1 research through 11 semi-structured interviews and document analyses. Data analysis led to 12 themes that responded to the research questions. Along with the literature and a focus group, these findings informed the action step, which was designed, executed, and evaluated in Cycle 2. The action step involved four longtime remote workers sharing their lived experiences around remote work, breaks, and activity through a podcast series. These podcasts were consumed by 16 new remote workers who answered qualitative survey questions to determine the impact of the podcasts on their break taking during their workdays. The research found that a remote worker's work environment, degree of autonomy, and break options influence how they fit in breaks during their workdays. The findings suggest that remote workers need consistent organizational support;that having autonomy to manage their workdays is critical for remote workers;and all breaks "are not created equal". (PsycInfo Database Record (c) 2023 APA, all rights reserved)
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Investors' trading activities are influenced by their financial attitudes. Even though existing research has recognized and investigated their relationship, behavioral assessments and financial attitude still poses questions. Furthermore, there is a lack of evidence about the trading activity of retail investors in the instance of a health crisis, like COVID-19 pandemic. The aim of study is to fill in the gaps in the existing literature by studying the relative impact of five dimensions of financial attitude on trading activity of retail investors' during the pandemic. We have used five dimensions to measure financial attitude such as financial anxiety, optimism of investors, financial security, self-control, and the need for precautionary savings. We collected 512 responses from retail investors with the help of a structured questionnaire. We analyzed financial attitude and trading activity using SEM to establish the structural relationship. The observed findings disclosed that self-control is the dominant variable followed by financial security, need for precautionary savings, financial anxiety, and optimism. © 2022, School of Management Sciences. All rights reserved.
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The Covid-19 pandemic forced the world population to incorporate prevention activities into their daily lives to preserve people's physical health. In Colombia, the national government, through resolutions and decrees, regulated quarantine and preventive isolation in order not to saturate health services and intensive care units, which were not prepared to respond to the disease. In this sense, this article analyzed the habits of physical activity, well-being, and quality of life in preventive isolation - Covid-19 in Bogota, Colombia. A cross-sectional descriptive quantitative study was conducted on a sample of 1,775 people with an average age of 43.5+or-25.5 years, of which 50.9% (n=903) corresponded to women and 49.1% (n=872) to men. It was found that due to the confinement the consumption of coffee and alcoholic beverages increased, as well as a decrease in physical activity. In addition, manifestations of anxiety, depression and feelings of loneliness were identified, which directly affected people's well-being and quality of life. It is expected that this type of research will contribute to the understanding of the impact of the contingency measures taken by the different nations to curb Covid-19 infections on people's health.
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Purpose: In addition to its psychologically and socially negative effects on society, the COVID-19 pandemic has affected the sexual behavior of individuals. This study investigated the relationship between changes in sexual drive and well-being during the COVID-19 pandemic period. Materials and methods: The data of this cross-sectional study were collected using a web-based survey between May 12 and August 12, 2021, with the voluntary participation of 231 individuals. The survey form included questions on sociodemographic and health-related characteristics, employment status, sex life before and during the COVID-19 pandemic period and status of having a partner, and COVID-19 diagnostic status, in addition to the Short Warwick-Edinburgh Mental Well-Being Scale. Results: A reduction in sexual drive in the pandemic period was reported by 71 (30.7%) participants. The group whose sexual drive decreased had significant differences in terms of age, marital status, the status of having children, and Warwick-Edinburgh scale scores compared to the groups whose sexual drive increased or remained unchanged (respectively, p=0.009, p=0.039, p=0.041, and p<0.001). According to the logistic regression model, for every one-year increase in age corresponded to 8% (95% CI: 3-12%) increase in the risk of reduced sexual drive (p=0.001), and a 1-unit increase in Warwick-Edinburgh scale scores corresponded to a 16% (95% CI: 10-22%) decrease (p<0.001). Conclusion: The COVID-19 pandemic affected the sexual drives and behavior of the participants. Increased age and lower mental well-being levels were associated with lower sexual drive. Programs aimed at improving mental well-being will have a beneficial effect on sexual behavior. © 2023, Pamukkale University. All rights reserved.
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Background and aimsMajority of elective orthopaedic operations are postponed to accommodate the reallocation of healthcare resources to combat the pandemic. The aim of this paper is to evaluate the mental state of orthopaedic patients amidst limited orthopaedic management options. The secondary aim of this paper is to identify areas of significant stressors and to provide avenues for improvements.MethodsA survey was administered on patients in outpatient clinics within a tertiary institution from 31 May to 13 June 2021 where government interventions prevented elective orthopaedic surgeries from being performed. Individuals' fatigue level were assessed with Chalder fatigue scale (CFS) and they were surveyed on their areas of stressors.ResultsA total of 160 orthopaedic patients (67 males and 93 females) were surveyed with an average age of 48.3 years old (range 17-88). 65 out of 160 (40.6%) were deemed to be severely fatigued (CFS > 4) with a higher prevalence amongst females than males (47.3% vs 31.3% respectively.) The top three areas identified as stressors included transmitting to family/friends, travel restrictions/quarantine orders and limitation on recreational/social activities (67.5%, 45.6% and 57.5% respectively). 25.6% of the patients indicated that the increased difficulty in accessing healthcare was a stress factor.Discussion and conclusionThere is a high proportion of severe fatigue amongst orthopaedic patients. Combined with postponement of orthopaedic care and treatment, the detrimental effects of a prolong pandemic can be more pronounced on orthopaedic patients. Identified areas of stressors provide avenues for improvements to safeguard the mental health of orthopaedic patients.